DISEASES

Disease-gene associations mined from literature

Literature on CARMIL1

CARMIL1 [ENSP00000331983]

F-actin-uncapping protein LRRC16A; Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments . Plays a role in lamellipodial protrusion formations and cell migration ; Belongs to the CARMIL family.

Synonyms:  CARMIL1,  CARMIL1p,  hCARMIL1,  A0A0U1RQQ1,  A0A0U1RR91 ...

Linkouts:  STRING  Pharos  UniProt  OMIM