DISEASES

Disease-gene associations mined from literature

Literature on PCM1

PCM1 [ENSP00000327077]

Pericentriolar material 1 protein; Required for centrosome assembly and function . Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2 . Required to anchor microtubules to the centrosome (PubMed:12403812, PubMed:15659651). Involved in the biogenesis of cilia (PubMed:20551181, PubMed:24121310). ECO:0000269|PubMed:15659651, ECO:0000269|PubMed:16943179,; Belongs to the PCM1 family.

Synonyms:  PCM1,  PCM1p,  hPCM1,  A0A4W8VX11,  E5RGQ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM