DISEASES

Disease-gene associations mined from literature

Literature on PRSS8

PRSS8 [ENSP00000319730]

Prostasin heavy chain; Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).

Synonyms:  PRSS8,  PRSS8p,  hPRSS8,  H3BUJ8,  H3BVC8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM