DISEASES

Disease-gene associations mined from literature

Literature on ING2

ING2 [ENSP00000307183]

Inhibitor of growth protein 2; Seems to be involved in p53/TP53 activation and p53/TP53- dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

Synonyms:  ING2,  ING2p,  hING2,  C9J4X5,  Q9H160 ...

Linkouts:  STRING  Pharos  UniProt  OMIM