Literature on KREMEN2
KREMEN2 [ENSP00000304422]
Kremen protein 2; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.
Synonyms: KREMEN2, KREMEN2p, hKREMEN2, Q8NCW0, Q8NCW0p ...