DISEASES

Disease-gene associations mined from literature

Literature on LRR1

LRR1 [ENSP00000298288]

Leucine-rich repeat protein 1; May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Synonyms:  LRR1,  LRR1p,  hLRR1,  A0A384MTQ0,  G3V5H2 ...

Linkouts:  STRING  Pharos  UniProt