DISEASES

Disease-gene associations mined from literature

Literature on LRRC14

LRRC14 [ENSP00000292524]

Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily.

Synonyms:  LRRC14,  LRRC14p,  hLRRC14,  E9PNL0,  E9PP40 ...

Linkouts:  STRING  Pharos  UniProt