DISEASES

Disease-gene associations mined from literature

Literature on DKKL1

DKKL1 [ENSP00000221498]

Dickkopf-like protein 1; Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduces testosterone synthesis in Leydig cells. Is not essential either for development or fertility.

Synonyms:  DKKL1,  DKKL1p,  hDKKL1,  A0A140VK15,  M0QYJ2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM