DISEASES

Disease-gene associations mined from literature

Literature on EIF5

EIF5 [ENSP00000216554]

Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

Synonyms:  EIF5,  EIF5p,  hEIF5,  A0A024R6Q1,  H0YK11 ...

Linkouts:  STRING  Pharos  UniProt  OMIM