DISEASES

Disease-gene associations mined from literature

Literature on PLA2G3

PLA2G3 [ENSP00000215885]

Group 3 secretory phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Shows an 11-fold preference for phosphatidylglycerol over phosphatidylcholine (PC). Preferential cleavage: 1-palmitoyl-2-linoleoyl-phosphatidylethanolamine (PE) > 1- palmitoyl-2-linoleoyl-PC > 1-palmitoyl-2-arachidonoyl-PC > 1-palmitoyl- 2-arachidonoyl-PE. Plays a role in ciliogenesis.

Synonyms:  PLA2G3,  PLA2G3p,  hPLA2G3,  Q9NZ20,  Q9NZ20p ...

Linkouts:  STRING  Pharos  UniProt  OMIM