DISEASES

Disease-gene associations mined from literature

Literature on GSTA3

GSTA3 [ENSP00000211122]

Glutathione S-transferase A3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively.

Synonyms:  GSTA3,  GSTA3p,  hGSTA3,  Q16772,  Q5JW84 ...

Linkouts:  STRING  Pharos  UniProt  OMIM