DISEASES

Disease-gene associations mined from literature

Literature on CDC25B

CDC25B [ENSP00000245960]

M-phase inducer phosphatase 2; Tyrosine protein phosphatase which functions as a dosage- dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2- dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Synonyms:  CDC25B,  CDC25Bp,  hCDC25B,  B4DIG0,  G8JLH2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM