DISEASES

Disease-gene associations mined from literature

Literature on CDCA2

CDCA2 [ENSP00000328228]

Cell division cycle-associated protein 2; Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Synonyms:  CDCA2,  CDCA2p,  hCDCA2,  E9PEI0,  Q69YH5 ...

Linkouts:  STRING  Pharos  UniProt