DISEASES

Disease-gene associations mined from literature

Literature on GLS

GLS [ENSP00000317379]

Glutaminase kidney isoform, mitochondrial 65 kDa chain; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain (PubMed:30575854, PubMed:30239721, PubMed:30970188); Belongs to the glutaminase family.

Synonyms:  GLS,  B7Z509,  B8ZZA8,  B8ZZC5,  C9JIJ6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM