DISEASES

Disease-gene associations mined from literature

Literature on PFN2

PFN2 [ENSP00000239940]

Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Synonyms:  PFN2,  PFN2p,  hPFN2,  C9J0J7,  C9J2N0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM