DISEASES

Disease-gene associations mined from literature

Literature on APOBEC1

APOBEC1 [ENSP00000229304]

C->U-editing enzyme APOBEC-1; Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation; Belongs to the cytidine and deoxycytidylate deaminase family.

Synonyms:  APOBEC1,  APOBEC1p,  hAPOBEC1,  A0A0B4J232,  P41238 ...

Linkouts:  STRING  Pharos  UniProt  OMIM