Literature on SLF2
SLF2 [ENSP00000359292]
SMC5-SMC6 complex localization factor protein 2; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance . The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks . Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions ; Belongs to the FAM178 family.
Synonyms: SLF2, SLF2p, hSLF2, A0A3B3IRS8, B1AL16 ...