DISEASES

Disease-gene associations mined from literature

Literature on DHCR24

DHCR24 [ENSP00000360316]

Delta(24)-sterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:25637936, PubMed:22178193). In addition to its cholesterol-synthesizing activity, can protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress . Also protects against amyloid-beta peptide-induced apoptosis . ECO:0000269|PubMed:21671375, ECO:0000269|PubMed:22010141,

Synonyms:  DHCR24,  DHCR24p,  hDHCR24,  A0A0A0MTI1,  A0A3B3IRV7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM