DISEASES

Disease-gene associations mined from literature

Literature on LRIF1

LRIF1 [ENSP00000358778]

Ligand-dependent nuclear receptor-interacting factor 1; Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin . Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases .

Synonyms:  LRIF1,  LRIF1p,  hLRIF1,  Q5T3J3,  Q5T3J3p ...

Linkouts:  STRING  Pharos  UniProt