DISEASES

Disease-gene associations mined from literature

Literature on LRRFIP2

LRRFIP2 [ENSP00000338727]

Leucine-rich repeat flightless-interacting protein 2; May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding; Belongs to the LRRFIP family.

Synonyms:  LRRFIP2,  LRRFIP2p,  hLRRFIP2,  C9J0U5,  C9J321 ...

Linkouts:  STRING  Pharos  UniProt  OMIM