DISEASES

Disease-gene associations mined from literature

Literature on RNF144A

RNF144A [ENSP00000321330]

E3 ubiquitin-protein ligase RNF144A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC; Belongs to the RBR family. RNF144 subfamily.

Synonyms:  RNF144A,  RNF144Ap,  hRNF144A,  C9JLH4,  H7C3G0 ...

Linkouts:  STRING  Pharos  UniProt