DISEASES

Disease-gene associations mined from literature

Literature on ERN2

ERN2 [ENSP00000256797]

Serine/threonine-protein kinase/endoribonuclease IRE2; Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

Synonyms:  ERN2,  E7ETG2,  ERN2p,  hERN2,  H3BSU1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM