DISEASES

Disease-gene associations mined from literature

Literature on GNL2

GNL2 [ENSP00000362153]

Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels .

Synonyms:  GNL2,  GNL2p,  hGNL2,  H0YG10,  Q13823 ...

Linkouts:  STRING  Pharos  UniProt  OMIM