DISEASES

Disease-gene associations mined from literature

Literature on MAP2K3

MAP2K3 [ENSP00000345083]

Dual specificity mitogen-activated protein kinase kinase 3; Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

Synonyms:  MAP2K3,  MAP2K3p,  hMAP2K3,  E9PMA8,  E9PRZ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM