DISEASES

Disease-gene associations mined from literature

Literature on GPHA2

GPHA2 [ENSP00000279168]

Glycoprotein hormone alpha-2; Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production . Plays a central role in controlling thyroid cell metabolism . ; Belongs to the glycoprotein hormones subunit alpha family.

Synonyms:  GPHA2,  GPHA2p,  hGPHA2,  A0A024R579,  E9PLQ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM