DISEASES

Disease-gene associations mined from literature

Literature on N4BP1

N4BP1 [ENSP00000262384]

NEDD4-binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity); Belongs to the N4BP1 family.

Synonyms:  N4BP1,  N4BP1p,  hN4BP1,  I3L3R7,  O75113 ...

Linkouts:  STRING  Pharos  UniProt