DISEASES

Disease-gene associations mined from literature

Literature on TMCC1

TMCC1 [ENSP00000376930]

Transmembrane and coiled-coil domains protein 1; Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission . Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission . Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane . ; Belongs to the TEX28 family.

Synonyms:  TMCC1,  TMCC1p,  hTMCC1,  D6RBT7,  D6RH19 ...

Linkouts:  STRING  Pharos  UniProt