DISEASES

Disease-gene associations mined from literature

Literature on CCNL1

CCNL1 [ENSP00000295926]

Cyclin-L1; Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) . Inhibited by the CDK-specific inhibitor CDKN1A/p21 . May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto- oncogene in head and neck squamous cell carcinomas (HNSCC) . ECO:0000269|PubMed:12414649, ECO:0000269|PubMed:15700036,

Synonyms:  CCNL1,  CCNL1p,  hCCNL1,  H7C4G1,  Q9UK58 ...

Linkouts:  STRING  Pharos  UniProt  OMIM