DISEASES

Disease-gene associations mined from literature

Literature on TCEAL7

TCEAL7 [ENSP00000329794]

Transcription elongation factor A protein-like 7; Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.

Synonyms:  TCEAL7,  TCEAL7p,  hTCEAL7,  Q9BRU2,  Q9BRU2p ...

Linkouts:  STRING  Pharos  UniProt  OMIM