DISEASES

Disease-gene associations mined from literature

Literature on ZDHHC19

ZDHHC19 [ENSP00000296326]

Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS . Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer . Palmitoylation of RRAS is linked to cell viability . May be involved in S-stearoylation of STAT3 (Probable).

Synonyms:  ZDHHC19,  ZDHHC19p,  hZDHHC19,  A0A0B4J1W2,  Q8WVZ1 ...

Linkouts:  STRING  Pharos  UniProt