DISEASES

Disease-gene associations mined from literature

Literature on KCNIP2

KCNIP2 [ENSP00000420040]

Kv channel-interacting protein 2; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity). ECO:0000269|PubMed:11287421, ECO:0000269|PubMed:11684073, ECO:0000269|PubMed:12297301, ECO:0000269|PubMed:12829703,

Synonyms:  KCNIP2,  KCNIP2p,  hKCNIP2,  A0A2R8Y6D7,  A6NFF4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM