DISEASES

Disease-gene associations mined from literature

Literature on IL17RD

IL17RD [ENSP00000296318]

Interleukin-17 receptor D; Feedback inhibitor of fibroblast growth factor mediated Ras- MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity).

Synonyms:  IL17RD,  IL17RDp,  hIL17RD,  C9J6R0,  Q8NFM7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM