Literature on ERAP2
ERAP2 [ENSP00000400376]
Endoplasmic reticulum aminopeptidase 2; Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Synonyms: ERAP2, ERAP2p, hERAP2, D6RF46, D6RGW0 ...