DISEASES

Disease-gene associations mined from literature

Literature on H1-4

H1-4 [ENSP00000307705]

Histone H1.4; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Synonyms:  H1-4,  A3R0T8,  HIST1H1E,  P10412,  A3R0T8p ...

Linkouts:  STRING  Pharos  UniProt  OMIM