DISEASES

Disease-gene associations mined from literature

Literature on GRIK3

GRIK3 [ENSP00000362183]

Glutamate receptor ionotropic, kainate 3; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.

Synonyms:  GRIK3,  GRIK3p,  hGRIK3,  Q13003,  Q13003p ...

Linkouts:  STRING  Pharos  UniProt  OMIM