DISEASES

Disease-gene associations mined from literature

Literature on HENMT1

HENMT1 [ENSP00000359049]

Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Synonyms:  HENMT1,  HENMT1p,  hHENMT1,  A0A0A0MRN1,  Q5T8I9 ...

Linkouts:  STRING  Pharos  UniProt