DISEASES

Disease-gene associations mined from literature

Literature on NPPA

NPPA [ENSP00000365663]

Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Synonyms:  NPPA,  A0A087X094,  B0ZBE8,  P01160,  B0ZBE8p ...

Linkouts:  STRING  Pharos  UniProt  OMIM