DISEASES

Disease-gene associations mined from literature

Literature on TMEM266

TMEM266 [ENSP00000373594]

Transmembrane protein 266; Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum . Despite the presence of a voltage- sensor segment, does not form a functional ion channel and its precise role remains unclear . Undergoes both rapid and slow structural rearrangements in response to changes in voltage . Contains a zinc-binding site that can regulate the slow conformational transition .

Synonyms:  TMEM266,  TMEM266p,  hTMEM266,  H0YNC9,  H3BM28 ...

Linkouts:  STRING  Pharos  UniProt