DISEASES

Disease-gene associations mined from literature

Literature on HOOK1

HOOK1 [ENSP00000360252]

Protein Hook homolog 1; Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) .

Synonyms:  HOOK1,  HOOK1p,  hHOOK1,  B1AK95,  Q9UJC3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM