DISEASES

Disease-gene associations mined from literature

Literature on WASHC3

WASHC3 [ENSP00000240079]

WASH complex subunit 3; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093); Belongs to the CCDC53 family.

Synonyms:  WASHC3,  WASHC3p,  hWASHC3,  F5GWI9,  F5GXZ4 ...

Linkouts:  STRING  Pharos  UniProt