DISEASES

Disease-gene associations mined from literature

Literature on RNF182

RNF182 [ENSP00000420465]

E3 ubiquitin-protein ligase RNF182; E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway . Plays also a role in the inhibition of TLR- triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA .

Synonyms:  RNF182,  RNF182p,  hRNF182,  A0A024QZW5,  C9IZ30 ...

Linkouts:  STRING  Pharos  UniProt