Literature on SPAG8
SPAG8 [ENSP00000340982]
Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis . May play a role in fertility and microtubule formation through interaction with RANBP9 .
Synonyms: SPAG8, SPAG8p, hSPAG8, A0A140VJV0, C9JAA8 ...