DISEASES

Disease-gene associations mined from literature

Literature on SLFN13

SLFN13 [ENSP00000285013]

Schlafen family member 13; Endoribonuclease that cleaves tRNAs and rRNAs . Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem . Does not act on tRNA(Sec) . Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity .

Synonyms:  SLFN13,  SLFN13p,  hSLFN13,  E9PKT7,  E9PM29 ...

Linkouts:  STRING  Pharos  UniProt  OMIM