DISEASES

Disease-gene associations mined from literature

Literature on LRRTM2

LRRTM2 [ENSP00000274711]

Leucine-rich repeat transmembrane neuronal protein 2; Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).

Synonyms:  LRRTM2,  LRRTM2p,  hLRRTM2,  E5RHE5,  E5RIQ2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM