DISEASES

Disease-gene associations mined from literature

Literature on MEIS1

MEIS1 [ENSP00000272369]

Homeobox protein Meis1; Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.

Synonyms:  MEIS1,  MEIS1p,  hMEIS1,  E9PDC4,  F5GYS8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM