DISEASES

Disease-gene associations mined from literature

Literature on PPP2R5B

PPP2R5B [ENSP00000164133]

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.

Synonyms:  PPP2R5B,  PPP2R5Bp,  hPPP2R5B,  A0A024R593,  E9PNY3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM