DISEASES

Disease-gene associations mined from literature

Literature on GBP1

GBP1 [ENSP00000359504]

Guanylate-binding protein 1; Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

Synonyms:  GBP1,  GBP1p,  hGBP1,  P32455,  P32455p ...

Linkouts:  STRING  Pharos  UniProt  OMIM