DISEASES

Disease-gene associations mined from literature

Literature on NLGN3

NLGN3 [ENSP00000351591]

Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity); Belongs to the type-B carboxylesterase/lipase family.

Synonyms:  NLGN3,  NLGN3p,  hNLGN3,  A0A087WW27,  E7EVK0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM