DISEASES

Disease-gene associations mined from literature

Literature on SMC4

SMC4 [ENSP00000341382]

Structural maintenance of chromosomes protein 4; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Synonyms:  SMC4,  SMC4p,  hSMC4,  C9IYK2,  C9J578 ...

Linkouts:  STRING  Pharos  UniProt  OMIM