DISEASES

Disease-gene associations mined from literature

Literature on TRIM9

TRIM9 [ENSP00000298355]

E3 ubiquitin-protein ligase TRIM9; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. ; Belongs to the TRIM/RBCC family.

Synonyms:  TRIM9,  TRIM9p,  hTRIM9,  Q9C026,  Q9C026p ...

Linkouts:  STRING  Pharos  UniProt  OMIM